Dosing and infusion

Stop the progression of SMA with a one-time-only infusion

ZOLGENSMA is a suspension administered as an intravenous infusion over 60 minutes. A programmable syringe pump should be used to infuse the full volume of ZOLGENSMA.1

How ZOLGENSMA is supplied

ZOLGENSMA is provided as a kit customized to meet weight-based dosing requirements for individual patients.1

See the preparation, dosing, and infusion process for ZOLGENSMA

Download the ZOLGENSMA Treatment Guide

Take an in-depth look at the steps to treatment and learn how to store, handle, and infuse ZOLGENSMA.

The recommended dose of ZOLGENSMA is 1.1 × 1014 vector genomes per kilogram (vg/kg) of body weight.1 Review the ZOLGENSMA Treatment Guide and the Full Prescribing Information for further dosing details

ZOLGENSMA Treatment Guide


Systemic corticosteroid regimen

To help manage a possible increase in liver aminotransferases following infusion with ZOLGENSMA, all patients should receive systemic corticosteroids prior to and following ZOLGENSMA infusion, as recommended1:

The recommended treatment regimen is detailed in the Prescribing Information and in the accompanying chart.


View Important Safety Information